Role of Helical Structure in MBP Immunodominant Peptides for Efficient IgM Antibody Recognition in Multiple Sclerosis

The involvement of Myelin Basic Protein (MBP) in Multiple Sclerosis (MS) has been widely discussed in the literature. This intrinsically disordered protein has an interesting α-helix motif, which can be considered as a conformational epitope. In this work we investigate the importance of the helical...

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Detalles Bibliográficos
Autores principales: Staśkiewicz, Agnieszka, Quagliata, Michael, Real-Fernandez, Feliciana, Nuti, Francesca, Lanzillo, Roberta, Brescia-Morra, Vincenzo, Rusche, Hendrik, Jewginski, Michal, Carotenuto, Alfonso, Brancaccio, Diego, Aharoni, Rina, Arnon, Ruth, Rovero, Paolo, Latajka, Rafal, Papini, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250970/
https://www.ncbi.nlm.nih.gov/pubmed/35795217
http://dx.doi.org/10.3389/fchem.2022.885180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250970/
https://www.ncbi.nlm.nih.gov/pubmed/35795217
http://dx.doi.org/10.3389/fchem.2022.885180

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