Downregulation of PLK4 expression induces apoptosis and G0/G1‐phase cell cycle arrest in keloid fibroblasts

OBJECTIVES: Keloids are benign fibroproliferative tumors that display many cancer‐like characteristics, such as progressive uncontrolled growth, lack of spontaneous regression, and extremely high rates of recurrence. Polo‐like kinase 4 (PLK4) was recently identified as a master regulator of centriol...

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Detalles Bibliográficos
Autores principales: Huang, Ru‐Lin, Liu, Chuanqi, Fu, Rao, Yan, Yuxin, Yang, Jing, Wang, Xinggang, Li, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251049/
https://www.ncbi.nlm.nih.gov/pubmed/35670224
http://dx.doi.org/10.1111/cpr.13271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251049/
https://www.ncbi.nlm.nih.gov/pubmed/35670224
http://dx.doi.org/10.1111/cpr.13271

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