Mitochondrial genome mutations and neuronal dysfunction of induced pluripotent stem cells derived from patients with Alzheimer's disease

OBJECTIVES: Patient‐derived induced pluripotent stem cells (iPSCs) are materials that can be used for autologous stem cell therapy. We screened mtDNA mutations in iPSCs and iPSC‐derived neuronal cells from patients with Alzheimer's disease (AD). Also, we investigated whether the mutations could...

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Detalles Bibliográficos
Autores principales: Lee, Yeonmi, Kim, Minchul, Lee, Miju, So, Seongjun, Kang, Soon‐Suk, Choi, Jiwan, Kim, Deokhoon, Heo, Hyohoon, Lee, Sung Soo, Park, Hee Ra, Ko, Jung Jae, Song, Jihwan, Kang, Eunju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251050/
https://www.ncbi.nlm.nih.gov/pubmed/35698260
http://dx.doi.org/10.1111/cpr.13274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251050/
https://www.ncbi.nlm.nih.gov/pubmed/35698260
http://dx.doi.org/10.1111/cpr.13274

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