Cargando…

Mitochondrial genome mutations and neuronal dysfunction of induced pluripotent stem cells derived from patients with Alzheimer's disease

OBJECTIVES: Patient‐derived induced pluripotent stem cells (iPSCs) are materials that can be used for autologous stem cell therapy. We screened mtDNA mutations in iPSCs and iPSC‐derived neuronal cells from patients with Alzheimer's disease (AD). Also, we investigated whether the mutations could...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Yeonmi, Kim, Minchul, Lee, Miju, So, Seongjun, Kang, Soon‐Suk, Choi, Jiwan, Kim, Deokhoon, Heo, Hyohoon, Lee, Sung Soo, Park, Hee Ra, Ko, Jung Jae, Song, Jihwan, Kang, Eunju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251050/ https://www.ncbi.nlm.nih.gov/pubmed/35698260 http://dx.doi.org/10.1111/cpr.13274

Ejemplares similares

Dysfunctional pancreatic cells differentiated from induced pluripotent stem cells with mitochondrial DNA mutations
por: So, Seongjun, et al.
Publicado: (2022)

Mitochondrial DNA Haplogroup Related to the Prevalence of Helicobacter pylori
por: Lee, Yeonmi, et al.
Publicado: (2021)

The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research
por: So, Seongjun, et al.
Publicado: (2020)

Artificial Oocyte: Development and Potential Application
por: Oqani, Reza K., et al.
Publicado: (2022)

Mitochondrial genome mutations in mesenchymal stem cells derived from human dental induced pluripotent stem cells
por: Park, Jumi, et al.
Publicado: (2019)

Therapeutic Potency of Induced Pluripotent Stem-Cell-Derived Corneal Endothelial-like Cells for Corneal Endothelial Dysfunction
por: So, Seongjun, et al.
Publicado: (2022)

De Novo Development of mtDNA Deletion Due to Decreased POLG and SSBP1 Expression in Humans
por: Lee, Yeonmi, et al.
Publicado: (2021)

The First Generation of iPSC Line from a Korean Alzheimer's Disease Patient Carrying APP-V715M Mutation Exhibits a Distinct Mitochondrial Dysfunction
por: Li, Ling, et al.
Publicado: (2019)

Efficient hepatic differentiation and regeneration potential under xeno-free conditions using mass-producible amnion-derived mesenchymal stem cells
por: Choi, Jiwan, et al.
Publicado: (2021)

Pathological manifestation of the induced pluripotent stem cell‐derived cortical neurons from an early‐onset Alzheimer's disease patient carrying a presenilin‐1 mutation (S170F)
por: Li, Ling, et al.
Publicado: (2020)

Stem cells and reproduction
por: Lee, Yeonmi, et al.
Publicado: (2019)

Long-term effects of human induced pluripotent stem cell-derived retinal cell transplantation in Pde6b knockout rats
por: Yang, Jee Myung, et al.
Publicado: (2021)

Selection of iPSCs without mtDNA deletion for autologous cell therapy in a patient with Pearson syndrome
por: Lee, Yeonmi, et al.
Publicado: (2023)

Hepatogenic Potential and Liver Regeneration Effect of Human Liver-derived Mesenchymal-Like Stem Cells
por: Lee, Jooyoung, et al.
Publicado: (2020)

Modeling of Frontotemporal Dementia Using iPSC Technology
por: Kim, Minchul, et al.
Publicado: (2020)

Effects and safety of intranasal phototherapy for allergic rhinitis: Study protocol for a single-center, randomized, parallel (acupuncture-controlled), open-label, investigator-initiated, pilot study
por: Kang, Jeongin, et al.
Publicado: (2020)

Haploidy in somatic cells is induced by mature oocytes in mice
por: Lee, Yeonmi, et al.
Publicado: (2022)

iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia
por: Li, Ling, et al.
Publicado: (2018)

Virulence factors released from Porphyromonas gingivalis induce electrophysiological dysfunction in human pluripotent stem cell-derived cardiomyocytes
por: Heo, Soon Chul, et al.
Publicado: (2022)

Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer’s disease
por: Lee, Seung-Eun, et al.
Publicado: (2022)

Protein‐Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease
por: Cha, Moon‐Yong, et al.
Publicado: (2016)

A Case Report of Early-Onset Alzheimer’s Disease Using (18)F-FDG PET and (18)F-FBB PET
por: Yoo, Jang, et al.
Publicado: (2023)

Modelling mitochondrial dysfunction in Alzheimer’s disease using human induced pluripotent stem cells
por: Hawkins, Kate Elizabeth, et al.
Publicado: (2019)

Dysfunction of Mitochondrial Dynamics in Drosophila Model of Diabetic Nephropathy
por: Kim, Kiyoung, et al.
Publicado: (2021)

The Outcomes and Quality of Pancreatic Islet Cells Isolated from Surgical Specimens for Research on Diabetes Mellitus
por: Oh, Ju Yun, et al.
Publicado: (2022)

Apigenin Ameliorates Scopolamine-Induced Cognitive Dysfunction and Neuronal Damage in Mice
por: Kim, Yeojin, et al.
Publicado: (2021)

Antioxidant Effects of Spinach (Spinacia oleracea L.) Supplementation in Hyperlipidemic Rats
por: Ko, Sang-Heui, et al.
Publicado: (2014)

AMOTL2 mono-ubiquitination by WWP1 promotes contact inhibition by facilitating LATS activation
por: Hwang, Daehee, et al.
Publicado: (2021)

Cognitive reserve proxies, Alzheimer pathologies, and cognition
por: Ko, Kang, et al.
Publicado: (2022)

Houttuynia cordata Improves Cognitive Deficits in Cholinergic Dysfunction Alzheimer’s Disease-Like Models
por: Huh, Eugene, et al.
Publicado: (2014)

Transcriptome comparison between pluripotent and non-pluripotent calli derived from mature rice seeds
por: Shim, Sangrea, et al.
Publicado: (2020)

Two Echinostome Species, Pegosomum bubulcum and Nephrostomum ramosum (Digenea: Echinostomatidae), from an Eastern Cattle Egret, Bubulcus ibis coromandus, in Republic of Korea
por: Choe, Seongjun, et al.
Publicado: (2016)

Early Diagnosis and Intervention Are Needed for a Reasonable Prognosis of Thromboangiitis Obliterans
por: Bae, Miju, et al.
Publicado: (2023)

Stereoscopic Depth Perception and Visuospatial Dysfunction in Alzheimer’s Disease
por: Kim, Nam-Gyoon, et al.
Publicado: (2021)

Usefulness of articulating laparoscopic instruments during laparoscopic gastrectomy for gastric adenocarcinoma
por: Lee, Eunju, et al.
Publicado: (2021)

Glymphatic system dysfunction in patients with early chronic kidney disease
por: Heo, Chang Min, et al.
Publicado: (2022)

Identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts
por: Park, Jihwan, et al.
Publicado: (2017)

Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease
por: Kim, Hye Yun, et al.
Publicado: (2014)

Revisiting the Bacterial Phylum Composition in Metabolic Diseases Focused on Host Energy Metabolism
por: Lee, Yeonmi, et al.
Publicado: (2020)

Direct Reprogramming of Rat Neural Precursor Cells and Fibroblasts into Pluripotent Stem Cells
por: Chang, Mi-Yoon, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_498hl9orc7k1mfsen1n1m03ksf