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Treacle is Upregulated in Cancer and Correlates With Poor Prognosis

Treacle/TCOF1 is an adaptor protein specifically associated with nucleolar chromatin. In the nucleolus it stimulates ribosome biogenesis, thereby promoting growth and proliferation. A second role of Treacle has emerged as a coordinator of the nucleolar responses to DNA damage, where it facilitates n...

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Detalles Bibliográficos
Autores principales: Oxe, Kezia Catharina, Larsen, Dorthe Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251355/
https://www.ncbi.nlm.nih.gov/pubmed/35794866
http://dx.doi.org/10.3389/fcell.2022.918544