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Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites
Gasdermins (GSDMs) are a group of proteins that are cleaved by inflammatory caspases to induce pore formation in the plasma membrane to cause membrane permeabilization and lytic cell death or pyroptosis. All GSDMs share a conserved structure, containing a cytotoxic N-terminal (NT) pore-forming domai...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251357/ https://www.ncbi.nlm.nih.gov/pubmed/35795683 http://dx.doi.org/10.3389/fimmu.2022.900553 |