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The ability of orexin-A to modify pain-induced cyclooxygenase-2 and brain-derived neurotrophic factor expression is associated with its ability to inhibit capsaicin-induced pulpal nociception in rats

BACKGROUND: The rostral ventromedial medulla (RVM) is a critical region for the management of nociception. The RVM is also involved in learning and memory processes due to its relationship with the hippocampus. The purpose of the present study was to investigate the molecular mechanisms behind orexi...

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Detalles Bibliográficos
Autores principales: Shahsavari, Fatemeh, Abbasnejad, Mehdi, Esmaeili-Mahani, Saeed, Raoof, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251390/
https://www.ncbi.nlm.nih.gov/pubmed/35768981
http://dx.doi.org/10.3344/kjp.2022.35.3.261