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Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Mitochondrial dysfunction has a role in sepsis-associated acute kidney injury (S-AKI), so the restoration of normal mitochondrial homeostasis may be an effective treatment strategy. Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) is a main regulator of cell-redox homeosta...

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Detalles Bibliográficos
Autores principales: Chen, Zhijiang, Wang, Huili, Hu, Bin, Chen, Xinxin, Zheng, Meiyu, Liang, Lili, Lyu, Juanjuan, Zeng, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251609/
https://www.ncbi.nlm.nih.gov/pubmed/35726572
http://dx.doi.org/10.4081/ejh.2022.3412