Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity

Background  Galectins have numerous cellular functions in immunity and inflammation. Short-term galectin-2 (Gal-2) blockade in ischemia-induced arteriogenesis shifts macrophages to an anti-inflammatory phenotype and improves perfusion. Gal-2 may also affect other macrophage-related cardiovascular di...

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Detalles Bibliográficos
Autores principales: Kane, Jamie, Jansen, Matthijs, Hendrix, Sebastian, Bosmans, Laura A., Beckers, Linda, Tiel, Claudia van, Gijbels, Marion, Zelcer, Noam, Vries, Carlie J. de, von Hundelshausen, Philipp, Vervloet, Marc, Eringa, Ed, Horrevoets, Anton J., Royen, Niels van, Lutgens, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251707/
https://www.ncbi.nlm.nih.gov/pubmed/34852377
http://dx.doi.org/10.1055/a-1711-1055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251707/
https://www.ncbi.nlm.nih.gov/pubmed/34852377
http://dx.doi.org/10.1055/a-1711-1055

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