Cargando…

Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity

Background Galectins have numerous cellular functions in immunity and inflammation. Short-term galectin-2 (Gal-2) blockade in ischemia-induced arteriogenesis shifts macrophages to an anti-inflammatory phenotype and improves perfusion. Gal-2 may also affect other macrophage-related cardiovascular di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kane, Jamie, Jansen, Matthijs, Hendrix, Sebastian, Bosmans, Laura A., Beckers, Linda, Tiel, Claudia van, Gijbels, Marion, Zelcer, Noam, Vries, Carlie J. de, von Hundelshausen, Philipp, Vervloet, Marc, Eringa, Ed, Horrevoets, Anton J., Royen, Niels van, Lutgens, Esther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251707/ https://www.ncbi.nlm.nih.gov/pubmed/34852377 http://dx.doi.org/10.1055/a-1711-1055

Ejemplares similares

Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single‐Domain Llama‐Derived Antibody
por: Hollander, Maurits R., et al.
Publicado: (2019)

CD40 in coronary artery disease: a matter of macrophages?
por: Jansen, Matthijs F., et al.
Publicado: (2016)

Atherosclerotic Plaque Destabilization in Mice: A Comparative Study
por: Hartwig, Helene, et al.
Publicado: (2015)

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
por: Baardman, Jeroen, et al.
Publicado: (2020)

Dendritic Cells in Human Atherosclerosis: From Circulation to Atherosclerotic Plaques
por: Van Vré, Emily A., et al.
Publicado: (2011)

Immuno-PET Imaging of Atherosclerotic Plaques with [(89)Zr]Zr-Anti-CD40 mAb—Proof of Concept
por: Poels, Kikkie, et al.
Publicado: (2022)

Atherosclerotic Plaque Biomarkers: Beyond the Horizon of the Vulnerable Plaque
por: W. van Lammeren, Guus, et al.
Publicado: (2011)

Imaging atherosclerotic plaques by targeting Galectin-3 and activated macrophages using ((89)Zr)-DFO- Galectin3-F(ab')(2) mAb
por: Varasteh, Zohreh, et al.
Publicado: (2021)

The marriage of chemokines and galectins as functional heterodimers
por: von Hundelshausen, Philipp, et al.
Publicado: (2021)

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics
por: Depuydt, Marie A.C., et al.
Publicado: (2020)

A Meta Analysis and Hierarchical Classification of HU-Based Atherosclerotic Plaque Characterization Criteria
por: Kristanto, Wisnumurti, et al.
Publicado: (2013)

Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke
por: He, Xin-Wei, et al.
Publicado: (2017)

Angiogenesis in the atherosclerotic plaque
por: Camaré, Caroline, et al.
Publicado: (2017)

Adipocytes control hematopoiesis and inflammation through CD40 signaling
por: Reiche, Myrthe E., et al.
Publicado: (2022)

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice
por: Poels, Kikkie, et al.
Publicado: (2020)

Galectin-2 Induces a Proinflammatory, Anti-Arteriogenic Phenotype in Monocytes and Macrophages
por: Yıldırım, Cansu, et al.
Publicado: (2015)

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice
por: Theelen, Thomas L., et al.
Publicado: (2015)

Intima heterogeneity in stress assessment of atherosclerotic plaques
por: Akyildiz, Ali C., et al.
Publicado: (2018)

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions
por: Hoeksema, Marten A, et al.
Publicado: (2014)

Radiofrequency Ablation of the Atherosclerotic Plaque: a Proof of Concept Study in an Atherosclerotic Model
por: Ellenbroek, Guilielmus H.J.M., et al.
Publicado: (2017)

Imaging the carotid atherosclerotic plaque
por: Neumann, Sandra, et al.
Publicado: (2019)

Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques
por: Hakimzadeh, Nazanin, et al.
Publicado: (2017)

Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays
por: Karel, M. F. A., et al.
Publicado: (2021)

Hyperlipidaemia elicits an atypical, T helper 1–like CD4(+) T-cell response: a key role for very low-density lipoprotein
por: van Os, Bram W, et al.
Publicado: (2023)

Impact of Alirocumab on Release Markers of Atherosclerotic Plaque Vulnerability in Patients with Mixed Hyperlipidemia and Vulnerable Atherosclerotic Plaque
por: Kosowski, Michał, et al.
Publicado: (2022)

The role of salivary galectin-3 and galectin-9 levels in plaque-induced gingivitis and periodontitis
por: Barut, Zerrin, et al.
Publicado: (2023)

Association of Lipoprotein(a) With Atherosclerotic Plaque Progression
por: Kaiser, Yannick, et al.
Publicado: (2022)

Cellular and Pharmacological Targets to Induce Coronary Arteriogenesis
por: Hollander, Maurits R., et al.
Publicado: (2014)

Osteopontin and osteoprotegerin in atherosclerotic plaque – are they significant markers of plaque vulnerability?
por: Strobescu-Ciobanu, Cristina, et al.
Publicado: (2020)

The Elusive Origin of Atherosclerotic Plaque Calcification
por: Canet-Soulas, Emmanuelle, et al.
Publicado: (2021)

Clinical Molecular Imaging for Atherosclerotic Plaque
por: Kondakov, Anton, et al.
Publicado: (2021)

Cellular crosstalk in atherosclerotic plaque microenvironment
por: Mahdinia, Elmira, et al.
Publicado: (2023)

Residual risks and evolving atherosclerotic plaques
por: Noothi, Sunil K., et al.
Publicado: (2023)

Small calcified coronary atherosclerotic plaque simulation model: minimal size and attenuation detectable by 64-MDCT and MicroCT
por: Kristanto, Wisnumurti, et al.
Publicado: (2011)

Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH
por: Aarts, Suzanne, et al.
Publicado: (2019)

Leukotriene B4 Levels in Human Atherosclerotic Plaques and Abdominal Aortic Aneurysms
por: van den Borne, Pleunie, et al.
Publicado: (2014)

Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice
por: Thiem, Kathrin, et al.
Publicado: (2019)

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation
por: Tang, Jun, et al.
Publicado: (2015)

Complement factor C5a induces atherosclerotic plaque disruptions
por: Wezel, Anouk, et al.
Publicado: (2014)

Effect of erythrophagocytosis-induced ferroptosis during angiogenesis in atherosclerotic plaques
por: Puylaert, Pauline, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_udbd0l9tgt730t55bifeeakpi5