Succinate metabolism in the retinal pigment epithelium uncouples respiration from ATP synthesis

Fumarate can be a surrogate for O(2) as a terminal electron acceptor in the electron transport chain. Reduction of fumarate produces succinate, which can be exported. It is debated whether intact tissues can import and oxidize succinate produced by other tissues. In a previous report, we showed that...

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Detalles Bibliográficos
Autores principales: Hass, Daniel T., Bisbach, Celia M., Robbings, Brian M., Sadilek, Martin, Sweet, Ian R., Hurley, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251713/
https://www.ncbi.nlm.nih.gov/pubmed/35675773
http://dx.doi.org/10.1016/j.celrep.2022.110917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251713/
https://www.ncbi.nlm.nih.gov/pubmed/35675773
http://dx.doi.org/10.1016/j.celrep.2022.110917

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