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Succinate metabolism in the retinal pigment epithelium uncouples respiration from ATP synthesis
Fumarate can be a surrogate for O(2) as a terminal electron acceptor in the electron transport chain. Reduction of fumarate produces succinate, which can be exported. It is debated whether intact tissues can import and oxidize succinate produced by other tissues. In a previous report, we showed that...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251713/ https://www.ncbi.nlm.nih.gov/pubmed/35675773 http://dx.doi.org/10.1016/j.celrep.2022.110917 |