Aminooxy Click Chemistry as a Tool for Bis-homo and Bis-hetero Ligand Conjugation to Nucleic Acids

[Image: see text] An aminooxy click chemistry (AOCC) strategy was used to synthesize nucleoside building blocks for incorporation during solid-support synthesis of oligonucleotides to enable bis-homo and bis-hetero conjugation of various biologically relevant ligands. The bis-homo aminooxy conjugati...

Descripción completa

Detalles Bibliográficos
Autores principales: Datta, Dhrubajyoti, Mori, Shohei, Madaoui, Mimouna, Wassarman, Kelly, Zlatev, Ivan, Manoharan, Muthiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251770/
https://www.ncbi.nlm.nih.gov/pubmed/35715221
http://dx.doi.org/10.1021/acs.orglett.2c00988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251770/
https://www.ncbi.nlm.nih.gov/pubmed/35715221
http://dx.doi.org/10.1021/acs.orglett.2c00988

Ejemplares similares