TLK1‐mediated MK5‐S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies

Metastases account for the majority of prostate cancer (PCa) deaths, and targeting them is a major goal of systemic therapy. We identified a novel interaction between two kinases: tousled‐like kinase 1 (TLK1) and MAP kinase‐activated protein kinase 5 (MK5) that promotes PCa spread. In PCa progressio...

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Detalles Bibliográficos
Autores principales: Khalil, Md Imtiaz, Singh, Vibha, King, Judy, De Benedetti, Arrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251878/
https://www.ncbi.nlm.nih.gov/pubmed/35064619
http://dx.doi.org/10.1002/1878-0261.13183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251878/
https://www.ncbi.nlm.nih.gov/pubmed/35064619
http://dx.doi.org/10.1002/1878-0261.13183

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