Trimeric receptor-binding domain of SARS-CoV-2 acts as a potent inhibitor of ACE2 receptor-mediated viral entry

The COVID-19 pandemic has caused over four million deaths and effective methods to control CoV-2 infection, in addition to vaccines, are needed. The CoV-2 binds to the ACE2 on human cells through the receptor-binding domain (RBD) of the trimeric spike protein. Our modeling studies show that a modifi...

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Detalles Bibliográficos
Autores principales: Basavarajappa, Shrikanth C., Liu, Angela Rose, Bruchez, Anna, Li, Zhenlu, Suzart, Vinicius G., Liu, Zhonghua, Chen, Yinghua, Xiao, Tsan Sam, Buck, Matthias, Ramakrishnan, Parameswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251894/
https://www.ncbi.nlm.nih.gov/pubmed/35813876
http://dx.doi.org/10.1016/j.isci.2022.104716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251894/
https://www.ncbi.nlm.nih.gov/pubmed/35813876
http://dx.doi.org/10.1016/j.isci.2022.104716

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