Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology

BACKGROUND: Adult microglia rely on self-renewal through division to repopulate and sustain their numbers. However, with aging, microglia display morphological and transcriptional changes that reflect a heightened state of neuroinflammation. This state threatens aging neurons and other cells and can...

Descripción completa

Detalles Bibliográficos
Autores principales: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252071/
https://www.ncbi.nlm.nih.gov/pubmed/35787714
http://dx.doi.org/10.1186/s12974-022-02532-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252071/
https://www.ncbi.nlm.nih.gov/pubmed/35787714
http://dx.doi.org/10.1186/s12974-022-02532-9

Ejemplares similares