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Engineering heterologous enzyme secretion in Yarrowia lipolytica

BACKGROUND: Eukaryotic cells are often preferred for the production of complex enzymes and biopharmaceuticals due to their ability to form post-translational modifications and inherent quality control system within the endoplasmic reticulum (ER). A non-conventional yeast species, Yarrowia lipolytica...

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Detalles Bibliográficos
Autores principales: Wang, Weigao, Blenner, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252082/
https://www.ncbi.nlm.nih.gov/pubmed/35786380
http://dx.doi.org/10.1186/s12934-022-01863-9