Curcumenol Mitigates the Inflammation and Ameliorates the Catabolism Status of the Intervertebral Discs In Vivo and In Vitro via Inhibiting the TNFα/NFκB Pathway

Low back pain (LBP) caused by intervertebral disc degeneration (IVDD) is accredited to the release of inflammatory cytokines followed by biomechanical and structural deterioration. In our study, we used a plant-derived medicine, curcumenol, to treat IVDD. A cell viability test was carried out to eva...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Li, Baixing, Tian, Haijun, Cheng, Xiaofei, Zhou, Tangjun, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252100/
https://www.ncbi.nlm.nih.gov/pubmed/35795557
http://dx.doi.org/10.3389/fphar.2022.905966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252100/
https://www.ncbi.nlm.nih.gov/pubmed/35795557
http://dx.doi.org/10.3389/fphar.2022.905966

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