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Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate

Arenaviruses are emerging enveloped negative-sense RNA viruses that cause neurological and hemorrhagic diseases in humans. Currently, no FDA-approved vaccine or therapeutic agent is available except for ribavirin, which must be administered early during infection for optimum efficacy. A hallmark of...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Hong Van, Yekwa, Elsie, Selisko, Barbara, Canard, Bruno, Alvarez, Karine, Ferron, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252148/
https://www.ncbi.nlm.nih.gov/pubmed/35844481
http://dx.doi.org/10.1107/S2052252522005061