The BET Inhibitor JQ1 Potentiates the Anticlonogenic Effect of Radiation in Pancreatic Cancer Cells

We reported previously that the BET inhibitor (BETi) JQ1 decreases levels of the DNA repair protein RAD51 and that this decrease is concomitant with increased levels of DNA damage. Based on these findings, we hypothesized that a BETi would augment DNA damage produced by radiation and function as a r...

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Detalles Bibliográficos
Autores principales: Garcia, Patrick L., Miller, Aubrey L., Zeng, Ling, van Waardenburg, Robert C. A. M., Yang, Eddy S., Yoon, Karina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252418/
https://www.ncbi.nlm.nih.gov/pubmed/35795040
http://dx.doi.org/10.3389/fonc.2022.925718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252418/
https://www.ncbi.nlm.nih.gov/pubmed/35795040
http://dx.doi.org/10.3389/fonc.2022.925718

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