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Impact of the Gastric Acid Suppressant Use on the Safety and Effectiveness of EGFR-TKIs: A Systematic Review and Meta-Analysis

Background The use of gastric acid suppressants (GASs) has an influence on the exposure of some epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and therefore may affect the effectiveness and safety of EGFR-TKIs. The impact of GASs, including proton pump inhibitors (PPIs) and...

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Detalles Bibliográficos
Autores principales: Du, Xin, Liu, Wei, Chen, Ken, Wang, Ziyu, Li, Xinyi, Yang, Li, Xie, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252455/
https://www.ncbi.nlm.nih.gov/pubmed/35795555
http://dx.doi.org/10.3389/fphar.2022.796538