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EZH2 Promotes T Follicular Helper Cell Differentiation Through Enhancing STAT3 Phosphorylation in Patients With Primary Sjögren’s Syndrome

OBJECTIVES: Enhancer of zeste homolog 2 (EZH2) is an epigenetic regulator that plays an essential role in immune system development and autoimmune diseases. This study aimed to characterize the role of EZH2 in the pathogenesis of primary Sjögren’s syndrome (pSS). METHODS: We analyzed EZH2 expression...

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Detalles Bibliográficos
Autores principales: He, Chengmei, Yang, Yanlei, Chen, Zhilei, Liu, Suying, Lyu, Taibiao, Zeng, Liuting, Wang, Li, Li, Yongzhe, Wang, Mu, Chen, Hua, Zhang, Fengchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252457/
https://www.ncbi.nlm.nih.gov/pubmed/35795677
http://dx.doi.org/10.3389/fimmu.2022.922871