A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions

RecA protein mediates homologous recombination repair in bacteria through assembly of long helical filaments on ssDNA in an ATP-dependent manner. RecX, an important negative regulator of RecA, is known to inhibit RecA activity by stimulating the disassembly of RecA nucleoprotein filaments. Here we u...

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Detalles Bibliográficos
Autores principales: Alekseev, Aleksandr, Pobegalov, Georgii, Morozova, Natalia, Vedyaykin, Alexey, Cherevatenko, Galina, Yakimov, Alexander, Baitin, Dmitry, Khodorkovskii, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252578/
https://www.ncbi.nlm.nih.gov/pubmed/35730924
http://dx.doi.org/10.7554/eLife.78409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252578/
https://www.ncbi.nlm.nih.gov/pubmed/35730924
http://dx.doi.org/10.7554/eLife.78409

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