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A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions
RecA protein mediates homologous recombination repair in bacteria through assembly of long helical filaments on ssDNA in an ATP-dependent manner. RecX, an important negative regulator of RecA, is known to inhibit RecA activity by stimulating the disassembly of RecA nucleoprotein filaments. Here we u...
Autores principales: | Alekseev, Aleksandr, Pobegalov, Georgii, Morozova, Natalia, Vedyaykin, Alexey, Cherevatenko, Galina, Yakimov, Alexander, Baitin, Dmitry, Khodorkovskii, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252578/ https://www.ncbi.nlm.nih.gov/pubmed/35730924 http://dx.doi.org/10.7554/eLife.78409 |
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