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A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks

Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends. To investigate the mechanisms behind network remodeling, we created a stochastic mo...

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Detalles Bibliográficos
Autores principales: Holz, Danielle, Hall, Aaron R, Usukura, Eiji, Yamashiro, Sawako, Watanabe, Naoki, Vavylonis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252579/
https://www.ncbi.nlm.nih.gov/pubmed/35670664
http://dx.doi.org/10.7554/eLife.69031