Ionizable Lipid Nanoparticle-Mediated Delivery of Plasmid DNA in Cardiomyocytes

INTRODUCTION: Gene therapy is a promising approach to be applied in cardiac regeneration after myocardial infarction and gene correction for inherited cardiomyopathies. However, cardiomyocytes are crucial cell types that are considered hard-to-transfect. The entrapment of nucleic acids in non-viral...

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Detalles Bibliográficos
Autores principales: Scalzo, Sérgio, Santos, Anderson K, Ferreira, Heloísa A S, Costa, Pedro A, Prazeres, Pedro H D M, da Silva, Natália J A, Guimarães, Lays C, e Silva, Mário de Morais, Rodrigues Alves, Marco T R, Viana, Celso T R, Jesus, Itamar C G, Rodrigues, Alice P, Birbrair, Alexander, Lobo, Anderson O, Frezard, Frederic, Mitchell, Michael J, Guatimosim, Silvia, Guimaraes, Pedro Pires Goulart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252585/
https://www.ncbi.nlm.nih.gov/pubmed/35795081
http://dx.doi.org/10.2147/IJN.S366962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252585/
https://www.ncbi.nlm.nih.gov/pubmed/35795081
http://dx.doi.org/10.2147/IJN.S366962

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