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CDK5 Mediates Proinflammatory Effects of Microglia through Activated DRP1 Phosphorylation in Rat Model of Intracerebral Hemorrhage

INTRODUCTION: Cyclin-dependent kinase-5 (CDK5) is a key kinase involved in brain development and function and recently found to be involved in neuronal and astroglial apoptosis, neural stem/progenitor cell stemness, mitochondrial fission, and synaptic transmission. But the specific mechanism of CDK5...

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Detalles Bibliográficos
Autores principales: He, Mingqing, Wang, Xiaoyan, Liu, Zheng, Cui, Qiyuan, Chen, Ying, Geng, Wenqing, Zhu, Jinzhou, Shen, Jiabing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252704/
https://www.ncbi.nlm.nih.gov/pubmed/35795154
http://dx.doi.org/10.1155/2022/1919064