FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid–liquid phase separation and aggregation of proteins

Many proteins perform their functions within membraneless organelles, where they form a liquid-like condensed state, also known as droplet state. The FuzDrop method predicts the probability of spontaneous liquid–liquid phase separation of proteins and provides a sequence-based score to identify the...

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Detalles Bibliográficos
Autores principales: Hatos, Andras, Tosatto, Silvio C E, Vendruscolo, Michele, Fuxreiter, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Web Server Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252777/
https://www.ncbi.nlm.nih.gov/pubmed/35610022
http://dx.doi.org/10.1093/nar/gkac386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252777/
https://www.ncbi.nlm.nih.gov/pubmed/35610022
http://dx.doi.org/10.1093/nar/gkac386

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