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Identification of genome edited cells using CRISPRnano

Genome engineering-induced cleavage sites can be resolved by non-homologous end joining (NHEJ) or homology-directed repair (HDR). Identifying genetically modified clones at the target locus remains an intensive and laborious task. Different workflows and software that rely on deep sequencing data ha...

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Detalles Bibliográficos
Autores principales: Nguyen, Thach, Ramachandran, Haribaskar, Martins, Soraia, Krutmann, Jean, Rossi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252781/
https://www.ncbi.nlm.nih.gov/pubmed/35640601
http://dx.doi.org/10.1093/nar/gkac440