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patcHwork: a user-friendly pH sensitivity analysis web server for protein sequences and structures

pH regulates protein function and interactions by altering the charge of individual residues causing loss or gain of intramolecular noncovalent bonds, which may lead to structural rearrangements. While tools to analyze residue-specific charge distribution of proteins at a given pH exist, currently n...

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Detalles Bibliográficos
Autores principales: Schmitz, Mirko, Schultze, Anne, Vanags, Raimonds, Voigt, Karsten, Di Ventura, Barbara, Öztürk, Mehmet Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252814/
https://www.ncbi.nlm.nih.gov/pubmed/35438792
http://dx.doi.org/10.1093/nar/gkac252