Secondary Metabolite Transcriptomic Pipeline (SeMa-Trap), an expression-based exploration tool for increased secondary metabolite production in bacteria

For decades, natural products have been used as a primary resource in drug discovery pipelines to find new antibiotics, which are mainly produced as secondary metabolites by bacteria. The biosynthesis of these compounds is encoded in co-localized genes termed biosynthetic gene clusters (BGCs). Howev...

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Detalles Bibliográficos
Autores principales: Mungan, Mehmet Direnç, Harbig, Theresa Anisja, Perez, Naybel Hernandez, Edenhart, Simone, Stegmann, Evi, Nieselt, Kay, Ziemert, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Web Server Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252823/
https://www.ncbi.nlm.nih.gov/pubmed/35580059
http://dx.doi.org/10.1093/nar/gkac371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252823/
https://www.ncbi.nlm.nih.gov/pubmed/35580059
http://dx.doi.org/10.1093/nar/gkac371

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