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High Levels of Hyaluronic Acid Synthase-2 Mediate NRF2-Driven Chemoresistance in Breast Cancer Cells

Hyaluronic acid (HA), a ligand of CD44, accumulates in some types of tumors and is responsible for tumor progression. The nuclear factor erythroid 2-like 2 (NRF2) regulates cytoprotective genes and drug transporters, which promotes therapy resistance in tumors. Previously, we showed that high levels...

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Detalles Bibliográficos
Autores principales: Choi, Bo-Hyun, Ryoo, Ingeun, Sim, Kyeong Hwa, Ahn, Hyeon-jin, Lee, Youn Ju, Kwak, Mi-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252875/
https://www.ncbi.nlm.nih.gov/pubmed/35768333
http://dx.doi.org/10.4062/biomolther.2022.074