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Repeated Morphine Administration Increases TRPV1 mRNA Expression and Autoradiographic Binding at Supraspinal Sites in the Pain Pathway

Repeated morphine administration induces tolerance to its analgesic effects. A previous study reported that repeated morphine treatment activates transient receptor potential vanilloid type 1 (TRPV1) expression in the sciatic nerve, dorsal root ganglion, and spinal cord, contributing to morphine tol...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi-Lien, Nam, Yun-Son, Lee, Seok-Yong, Jang, Choon-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252876/
https://www.ncbi.nlm.nih.gov/pubmed/35616070
http://dx.doi.org/10.4062/biomolther.2022.014