Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor Effects

Tropomyosin receptor kinase A (TrkA) protein is a receptor tyrosine kinase encoded by the NTRK1 gene. TrkA signaling mediates the proliferation, differentiation, and survival of neurons and other cells following stimulation by its ligand, the nerve growth factor. Chromosomal rearrangements of the NT...

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Detalles Bibliográficos
Autores principales: Lee, Hyo Jeong, Moon, Yeongyu, Choi, Jungil, Heo, Jeong Doo, Kim, Sekwang, Nallapaneni, Hari Krishna, Chin, Young-Won, Lee, Jongkook, Han, Sun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252884/
https://www.ncbi.nlm.nih.gov/pubmed/35264466
http://dx.doi.org/10.4062/biomolther.2021.195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252884/
https://www.ncbi.nlm.nih.gov/pubmed/35264466
http://dx.doi.org/10.4062/biomolther.2021.195

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