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Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver
Global obesity epidemics impacts human health and causes obesity-related illnesses, including the obesity-related kidney and liver diseases. UTX, a histone H3K27 demethylase, plays important roles in development and differentiation. Here we show that kidney-specific knockout Utx inhibits high-fat di...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253056/ https://www.ncbi.nlm.nih.gov/pubmed/35788583 http://dx.doi.org/10.1038/s41467-022-31476-0 |