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Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver

Global obesity epidemics impacts human health and causes obesity-related illnesses, including the obesity-related kidney and liver diseases. UTX, a histone H3K27 demethylase, plays important roles in development and differentiation. Here we show that kidney-specific knockout Utx inhibits high-fat di...

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Detalles Bibliográficos
Autores principales:	Chen, Hong, Liu, Chong, Wang, Qian, Xiong, Mingrui, Zeng, Xia, Yang, Dong, Xie, Yunhao, Su, Hua, Zhang, Yu, Huang, Yixue, Chen, Yuchen, Yue, Junqiu, Liu, Chengyu, Wang, Shun, Huang, Kun, Zheng, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253056/ https://www.ncbi.nlm.nih.gov/pubmed/35788583 http://dx.doi.org/10.1038/s41467-022-31476-0

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