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Development of an Immunohistochemical Assay for Siglec-15

Siglec-15, a member of sialic-acid binding immunoglobulin type lectins, is normally expressed by myeloid cells and upregulated in some human cancers and represents a promising new target for immunotherapy. While PD-L1 blockade is an important strategy for immunotherapy, its effectiveness is limited....

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Detalles Bibliográficos
Autores principales: Shafi, Saba, Aung, Thazin Nwe, Robbins, Charles, Zugazagoitia, Jon, Vathiotis, Ioannis, Gavrielatou, Niki, Yaghoobi, Vesal, Fernandez, Aileen, Niu, Shuqiong, Liu, Linda N., Cusumano, Zachary T., Leelatian, Nalin, Cole, Kimberley, Wang, He, Homer, Robert, Herbst, Roy S., Langermann, Sol, Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253057/
https://www.ncbi.nlm.nih.gov/pubmed/35459795
http://dx.doi.org/10.1038/s41374-022-00785-9