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Development of an Immunohistochemical Assay for Siglec-15
Siglec-15, a member of sialic-acid binding immunoglobulin type lectins, is normally expressed by myeloid cells and upregulated in some human cancers and represents a promising new target for immunotherapy. While PD-L1 blockade is an important strategy for immunotherapy, its effectiveness is limited....
Autores principales: | Shafi, Saba, Aung, Thazin Nwe, Robbins, Charles, Zugazagoitia, Jon, Vathiotis, Ioannis, Gavrielatou, Niki, Yaghoobi, Vesal, Fernandez, Aileen, Niu, Shuqiong, Liu, Linda N., Cusumano, Zachary T., Leelatian, Nalin, Cole, Kimberley, Wang, He, Homer, Robert, Herbst, Roy S., Langermann, Sol, Rimm, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253057/ https://www.ncbi.nlm.nih.gov/pubmed/35459795 http://dx.doi.org/10.1038/s41374-022-00785-9 |
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