Development and Evaluation of Novel Metformin Derivative Metformin Threonate for Brain Ischemia Treatment

Epidemiologic data reveal that diabetes patients taking metformin exhibit lower incidence of stroke and better functional outcomes during post-stroke neurologic recovery. We previously demonstrated that chronic post-ischemic administration of metformin improved functional recovery in experimental ce...

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Detalles Bibliográficos
Autores principales: Zhang, Gufang, Chen, Shuangshuang, Jia, Jia, Liu, Chun, Wang, Weipeng, Zhang, Hongjian, Zhen, Xuechu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253272/
https://www.ncbi.nlm.nih.gov/pubmed/35800435
http://dx.doi.org/10.3389/fphar.2022.879690