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Differential Activation of TRPM8 by the Stereoisomers of Menthol

The stereoisomers of menthol elicit cooling sensation to various levels. Though the high-resolution three-dimensional structures of the menthol receptor, the transient receptor potential melastatin 8 (TRPM8) ion channels, have been revolved in different states, the menthol-bound state structure is n...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoying, Xu, Lizhen, Zhang, Heng, Wen, Han, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253294/
https://www.ncbi.nlm.nih.gov/pubmed/35800442
http://dx.doi.org/10.3389/fphar.2022.898670