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Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice

The progressive destruction of condylar cartilage is a hallmark of the temporomandibular joint (TMJ) osteoarthritis (OA); however, its mechanism is incompletely understood. Here, we show that Kindlin-2, a key focal adhesion protein, is strongly detected in cells of mandibular condylar cartilage in m...

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Detalles Bibliográficos
Autores principales: Lai, Yumei, Zheng, Wei, Qu, Minghao, Xiao, Christopher C., Chen, Sheng, Yao, Qing, Gong, Weiyuan, Tao, Chu, Yan, Qinnan, Zhang, Peijun, Wu, Xiaohao, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253313/
https://www.ncbi.nlm.nih.gov/pubmed/35788130
http://dx.doi.org/10.1038/s41368-022-00185-1