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Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway

Osteoarthritis is a worldwide joint disease caused by abnormal chondrocytic metabolism. However, traditional therapeutic methods aimed at anti-inflammation for early-stage disease are palliative. In the present study, we demonstrated that cepharanthine (CEP), extracted from the plant Stephania cepha...

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Detalles Bibliográficos
Autores principales: Yao, Minjun, Zhang, Caihua, Ni, Lingzhi, Ji, Xiaoxiao, Hong, Jianqiao, Chen, Yazhou, Wang, Jie, Li, Congsun, Lin, Jiyan, Lu, Tingting, Sheng, Yihao, Sun, Menghao, Shi, Mingmin, Zhou, Chenhe, Cai, Xunzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253373/
https://www.ncbi.nlm.nih.gov/pubmed/35800437
http://dx.doi.org/10.3389/fphar.2022.854239