Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice

Duplication and haploinsufficiency of the USP7 gene are implicated in autism spectrum disorders (ASD), but the role for USP7 in neurodevelopment and contribution to ASD pathogenesis remain unknown. We find that in primary neurons, overexpression of USP7 increases dendritic branch number and total de...

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Detalles Bibliográficos
Autores principales: Qiao, Hui, Tian, Yuan, Huo, Yuda, Man, Heng-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253496/
https://www.ncbi.nlm.nih.gov/pubmed/35800757
http://dx.doi.org/10.1016/j.isci.2022.104595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253496/
https://www.ncbi.nlm.nih.gov/pubmed/35800757
http://dx.doi.org/10.1016/j.isci.2022.104595

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