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Emerging Role of CREB in Epithelial to Mesenchymal Plasticity of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive solid malignancy with a high rate of metastasis and therapeutic resistance as its major hallmarks. Although a defining mutational event in pancreatic cancer initiation is the presence of oncogenic KRAS, more advanced PDAC lesions accumulate ad...

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Detalles Bibliográficos
Autores principales: Mehra, Siddharth, Singh, Samara, Nagathihalli, Nagaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253527/
https://www.ncbi.nlm.nih.gov/pubmed/35800049
http://dx.doi.org/10.3389/fonc.2022.925687