Computer-Aided Design of α-L-Rhamnosidase to Increase the Synthesis Efficiency of Icariside I

Icariside I, the glycosylation product of icaritin, is a novel effective anti-cancer agent with immunological anti-tumor activity. However, very limited natural icariside I content hinders its direct extraction from plants. Therefore, we employed a computer-aided protein design strategy to improve t...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jia-Jun, Hu, Hao-Xuan, Lu, Yu-Jing, Bao, Ya-Dan, Zhou, Jin-Lin, Huang, Mingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253678/
https://www.ncbi.nlm.nih.gov/pubmed/35800333
http://dx.doi.org/10.3389/fbioe.2022.926829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253678/
https://www.ncbi.nlm.nih.gov/pubmed/35800333
http://dx.doi.org/10.3389/fbioe.2022.926829

Ejemplares similares