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Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system

Protein disulfide isomerases (PDIs) constitute a family of oxidoreductases promoting redox protein folding and quality control in the endoplasmic reticulum. PDIs catalyze disulfide bond formation, isomerization, and reduction, operating in concert with molecular chaperones to fold secretory cargoes...

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Detalles Bibliográficos
Autores principales: Medinas, Danilo B., Rozas, Pablo, Hetz, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253707/
https://www.ncbi.nlm.nih.gov/pubmed/35654139
http://dx.doi.org/10.1016/j.jbc.2022.102087