Cargando…

SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway

Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-dependent lipid peroxidation. Cancer cells differ in their sensitivity to ferroptosis. Here we showed that the Suppressor of fused homolog (SUFU), a critical component in Hedgehog signaling, regulates ferroptosis...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Kun, Du, Sha, Shen, Dachuan, Xiong, Zhipeng, Jiang, Ke, Liang, Dapeng, Wang, Jianxin, Xu, Huizhe, Hu, Lulu, Zhai, Xingyue, Jiang, Yuting, Xia, Zhiyu, Xie, Chunrui, Jin, Di, Cheng, Wei, Meng, Songshu, Wang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253713/
https://www.ncbi.nlm.nih.gov/pubmed/35800779
http://dx.doi.org/10.1016/j.isci.2022.104618