Potent neutralization by monoclonal human IgM against SARS‐CoV‐2 is impaired by class switch

To investigate the class‐dependent properties of anti‐viral IgM antibodies, we use membrane antigen capture activated cell sorting to isolate spike‐protein‐specific B cells from donors recently infected with SARS‐CoV‐2, allowing production of recombinant antibodies. We isolate 20, spike‐protein‐spec...

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Detalles Bibliográficos
Autores principales: Callegari, Ilaria, Schneider, Mika, Berloffa, Giuliano, Mühlethaler, Tobias, Holdermann, Sebastian, Galli, Edoardo, Roloff, Tim, Boss, Renate, Infanti, Laura, Khanna, Nina, Egli, Adrian, Buser, Andreas, Zimmer, Gert, Derfuss, Tobias, Sanderson, Nicholas S R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253785/
https://www.ncbi.nlm.nih.gov/pubmed/35548920
http://dx.doi.org/10.15252/embr.202153956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253785/
https://www.ncbi.nlm.nih.gov/pubmed/35548920
http://dx.doi.org/10.15252/embr.202153956

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