Design and synthesis of novel enantiopure Bis(5-Isoxazolidine) derivatives: insights into their antioxidant and antimicrobial potential via in silico drug-likeness, pharmacokinetic, medicinal chemistry properties, and molecular docking studies

A series of novel compounds, mono-5-isoxazolidines, and bis (5-isoxazolidines) derivatives, were prepared as bicycloadducts. The new series of isoxazolidines were designed and synthesized via 1,3-dipolar cycloaddition reaction of nitrones with 3,9-Divinyl-2,4,8,10-tetra oxaspiro (5-5) undecane in th...

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Detalles Bibliográficos
Autores principales: AL-Adhreai, Arwa, ALSaeedy, Mohammed, Alrabie, Ali, Al-Qadsy, Inas, Dawbaa, Sam, Alaizeri, ZabnAllah M., Alhadlaq, Hisham A., Al-Kubati, Abdulrahman, Ahamed, Maqusood, Farooqui, Mazahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253851/
https://www.ncbi.nlm.nih.gov/pubmed/35800717
http://dx.doi.org/10.1016/j.heliyon.2022.e09746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253851/
https://www.ncbi.nlm.nih.gov/pubmed/35800717
http://dx.doi.org/10.1016/j.heliyon.2022.e09746

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