Amelioration of experimental tendinopathy by lentiviral CD44 gene therapy targeting senescence-associated secretory phenotypes

CD44 exerts anti-senescence effects in many disease models. We examined senescence in tendinopathy and the effect of CD44 on senescence-associated secretory phenotypes (SASPs). Senescent markers were determined in human tendinopathic long head of bicep (LHB) and normal hamstring tendons. CD44 gene t...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Yao, Jou, I-Ming, Ko, Po-Yen, Hsu, Kai-Lan, Su, Wei-Ren, Kuo, Li-Chieh, Lee, Pei-Yuan, Wu, Chao-Liang, Wu, Po-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254001/
https://www.ncbi.nlm.nih.gov/pubmed/35846572
http://dx.doi.org/10.1016/j.omtm.2022.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254001/
https://www.ncbi.nlm.nih.gov/pubmed/35846572
http://dx.doi.org/10.1016/j.omtm.2022.06.006

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